2-((3-氯吡嗪-2-基)甲基)异吲哚啉-1,3-二酮合成路线 (共 3 条)
反应条件
hydrazine in dichloromethane T=20°C; Inert atmosphere;
参考文献
UNIVERSITY OF WASHINGTON; VAN VOORHIS, Wesley, C.; HOL, Wilhelmus, G.J.; LARSON, Eric, T.; MALY, Dustin, James; MERRITT, Ethan; OJO, Kayode, K.
Patent: WO2011/94628 A1, 2011 ;
Location in patent: Page/Page column 105-106 ;
WO 2011/094628 A1
反应条件
di-isopropyl azodicarboxylate in tetrahydrofuran
12 h;
参考文献
UNIVERSITY OF WASHINGTON; VAN VOORHIS, Wesley, C.; HOL, Wilhelmus, G.J.; LARSON, Eric, T.; MALY, Dustin, James; MERRITT, Ethan; OJO, Kayode, K.
Patent: WO2011/94628 A1, 2011 ;
Location in patent: Page/Page column 105 ;
WO 2011/094628 A1
反应条件
in N,N-dimethyl-formamide
T=60°C; 17 h;
参考文献
Mulvihill, Kristen Michelle; Castelhano, Arlindo L.
Patent: US2007/129547 A1, 2007 ;
Location in patent: Page/Page column 4 ;