1: 99 percent / various solvent(s) / 20 h / 230 °C 2: Chiracel OD / propan-2-ol; hexane 3: bis(trimethylsilyl)peroxide; LDA / tetrahydrofuran / 4 h / -40 °C 4: 27.9 mg / tetrahydrofuran / 2 h / -40 - 20 °C 5: 90 percent / H2 / Pd/C / methanol / 17 h / 25 °C / atmospheric pressure 6: 69 percent / NMO; TPAP; 4 Angstroem molecular sieves / CH2Cl2 / 0 - 25 °C 7: 69 percent / Lawesson's reagent / toluene / 4 h / Heating 8: 61 percent / Raney Ni / tetrahydrofuran / 2 h / 25 °C 9: 82 percent / H2; aq. HCl / PtO2 / methanol / 2 h / 25 °C / 2068.59 - 2327.17 Torr 10: 98 percent / Bu4NF / tetrahydrofuran / 0 - 25 °C 11: 62 percent / PPh3 / acetonitrile; CCl4 / 1 h / 70 °C 12: 43 percent / AlCl3; bis(2-methoxyethoxy)aluminium hydride / tetrahydrofuran 13: 83 percent / NaOAc / 2 h / 25 °C View Scheme

1: 99 percent / various solvent(s) / 20 h / 230 °C 2: Chiracel OD / propan-2-ol; hexane 3: bis(trimethylsilyl)peroxide; LDA / tetrahydrofuran / 4 h / -40 °C 4: 27.9 mg / tetrahydrofuran / 2 h / -40 - 20 °C 5: 90 percent / H2 / Pd/C / methanol / 17 h / 25 °C / atmospheric pressure 6: 69 percent / NMO; TPAP; 4 Angstroem molecular sieves / CH2Cl2 / 0 - 25 °C 7: 69 percent / Lawesson's reagent / toluene / 4 h / Heating 8: 61 percent / Raney Ni / tetrahydrofuran / 2 h / 25 °C 9: 82 percent / H2; aq. HCl / PtO2 / methanol / 2 h / 25 °C / 2068.59 - 2327.17 Torr 10: 98 percent / Bu4NF / tetrahydrofuran / 0 - 25 °C 11: 62 percent / PPh3 / acetonitrile; CCl4 / 1 h / 70 °C 12: 43 percent / AlCl3; bis(2-methoxyethoxy)aluminium hydride / tetrahydrofuran View Scheme