2-苄基四氢吡咯并[3,4-c]吡咯-1,3-二酮合成路线 （共 6 条）
反应条件
1: With 1-chloroethyl chlorocarbonate in dichloromethane T=0°C; 3 h; Heating / reflux; 2: With methanol 3 h; Heating / reflux;
参考文献
CHEMOCENTRYX, INC.
Patent: WO2005/84667 A1, 2005 ;
Location in patent: Page/Page column 71 ;
WO 2005/084667 A1
反应条件
hydrogen; palladium on activated charcoal in acetic acid T=55°C; P=2585.7 Torr; 18 h; Yield given;
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 321 - 329
反应条件
1: 88 percent / dicyclohexylcarbodiimide / tetrahydrofuran / Heating; overnight 2: 84 percent / tetrahydrofuran / 60 °C / overnight 3: 90 percent / SOCl2 / dimethylformamide / 0.75 h / 45 °C 4: H2 / 10percent Pd/C / acetic acid / 18 h / 55 °C / 2585.7 Torr View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 321 - 329
反应条件
1: 84 percent / tetrahydrofuran / 60 °C / overnight 2: 90 percent / SOCl2 / dimethylformamide / 0.75 h / 45 °C 3: H2 / 10percent Pd/C / acetic acid / 18 h / 55 °C / 2585.7 Torr View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 321 - 329
反应条件
1: 90 percent / SOCl2 / dimethylformamide / 0.75 h / 45 °C 2: H2 / 10percent Pd/C / acetic acid / 18 h / 55 °C / 2585.7 Torr View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 321 - 329
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran 5 h; Heating / reflux; 2: With potassium hydroxide in water
参考文献
BAYER AKTIENGESELLSCHAFT
Patent: WO2003/106450 A1, 2003 ;
Location in patent: Page column 53 ;
WO 03/106450 A1
