5-(4-氨基-3-甲氧基苄基)-1,3-噻唑烷-2,4-二酮合成路线 （共 3 条）
反应条件
hydrogenchloride in ethanol
20 h;
参考文献
Sohda; Mizuno; Hirata; Maki; Kawamatsu
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 2 p. 560 - 569
反应条件
1: 57.5 percent / AcONa / 2-methoxy-ethanol / 16 h / 100 °C
2: 64.7 percent / 6N HCl / ethanol / 20 h
View Scheme
参考文献
Sohda; Mizuno; Hirata; Maki; Kawamatsu
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 2 p. 560 - 569
反应条件
1: 1.) NaNO2, conc. HCl, 2.) Cu2O / 1.) H2O, acetone, 5 deg C, 15 min, 2.) H2O, acetone, 5 -> 35 deg C
2: 57.5 percent / AcONa / 2-methoxy-ethanol / 16 h / 100 °C
3: 64.7 percent / 6N HCl / ethanol / 20 h
View Scheme
参考文献
Sohda; Mizuno; Hirata; Maki; Kawamatsu
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 2 p. 560 - 569
