3-甲氧基-5-三氟甲基苯甲腈合成路线 （共 4 条）
反应条件
tert.-butylnitrite in DMF (N,N-dimethyl-formamide) T=100°C; 24 h;
参考文献
WO2005/100298 A1, ;
Page/Page column 67 ;
反应条件
in N,N-dimethyl-formamide T=100°C; 24 h;
参考文献
Glaxo Group Limited; Wan, Zehong; Long, Kai; Sang, Yingxia; Su, Xiaobo
Patent: US2014/179715 A1, 2014 ;
Location in patent: Paragraph 0376 ;
反应条件
1: With boron tribromide in dichloromethane T=0 - 20°C; 48 h; 2: With sodium hydrogencarbonate in dichloromethane
参考文献
WO2013/13503 A1, ;
Page/Page column 44 ;
WO 2013/013503 A1
反应条件
formic acid; platinum(IV) oxide in water
T=60°C; 0.5 h;
参考文献
MERCK and CO., INC.
Patent: WO2005/100298 A1, 2005 ;
Location in patent: Page/Page column 67 ;
