反应条件
1: 99 percent / CBr4, Ph3P / CH2Cl2 / 3 h / -60 - -20 °C
2: 1.) NaH, 2.) n-BuLi
3: 1.) NaH / 1.) ether, 0 deg C, 20 min, 2.) ether, RT, 1.5 h
4: 1.) CuI / 1.) ether, 0 deg C, 30 min, 2.) ether, -78 deg C, 3 h
5: 96 percent / diisobutylaluminum hydride / CH2Cl2 / 1 h / -78 °C
6: 94 percent / CBr4, Ph3P / CH2Cl2 / 3 h / -78 - -60 °C
7: 26 percent / KOH / H2O / 0.67 h
8: 70 percent / acetic acid / H2O / 0.17 h / 120 °C
View Scheme
参考文献
Chen, Kau-Ming; Semple, J. Edward; Joullie, Madeleine M.
Journal of Organic Chemistry, 1985 , vol. 50, # 21 p. 3997 - 4005
