反应条件
1: 1.) butyllithium / 1.) hexane, THF, -20 deg C, 2 h, 2.) hexane, THF, -50 deg C, 7 h
2: pyridine, 4-dimethylaminopyridine / diethyl ether / 0.83 h
3: 65 percent / AgBF4 / benzene / 2.5 h / 80 °C
4: 92 percent / pyridinium p-toluenesulfonate / ethanol / 4 h / 50 °C
5: 92 percent / trioctylphosphine, carbon tetrabromide / diethyl ether / 0.22 h / 0 °C
6: 1.) butyllithium, 2.) 3-methoxy-3-methylbut-1-ynylcopper
7: 1.) LiAlH4, 2.) PCC, AcONa / 1.) Et2O, 10 min, 2.) dichloromethane, RT, 1 h
8: 62 percent / P2I4 / 0.42 h / 0 °C
View Scheme
参考文献
Saimoto; Ohrai; Sashiwa; Shigemasa; Hiyama
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 9 p. 2727 - 2734
