反应条件
1: 2,2-Dimethyl-N-(4-methyl-2-pyridinyl)propanamide With tert.-butyl lithium in diethyl ether; pentane T=-78 - -10°C; 1.5 h; 2: 3-dimethylaminoacrylaldehyde in tetrahydrofuran; hexane T=-70 - 0°C; 3 h; 3: With hydrogenchloride T=80 - 90°C; 0.75 h;
参考文献
Zhichkin, Pavel; Beer, Catherine M. Cillo; Rennells, W. Martin; Fairfax, David J.
Synlett, 2006 , # 3 p. 379 - 382