3-(2,2-二甲基丙酰胺)-异烟酸合成路线 （共 4 条）
反应条件
n-butyllithium; N,N,N',N,-tetramethylethylenediamine in diethyl ether; hexane 1.) -10 degC, 2 h, 2.) 1 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 26, # 1 p. 105 - 112
反应条件
1: 73 percent / triethylamine / CH2Cl2 / 2 h / Ambient temperature 2: 1.) n-BuLi; 2.) ether/ice / 1.) THF, 0 deg C, 3h; 2.) -78 deg C to room temp. View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 20 p. 3401 - 3408
反应条件
1: 73 percent / triethylamine / CH2Cl2 / 2 h / Ambient temperature 2: 1.) n-BuLi; 2.) ether/ice / 1.) THF, 0 deg C, 3h; 2.) -78 deg C to room temp. View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 20 p. 3401 - 3408
反应条件
n-butyllithium; diethyl ether; d-N,a-dimethylphenethylamine 1.) THF, 0 deg C, 3h; 2.) -78 deg C to room temp.; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 48, # 20 p. 3401 - 3408
