4-(呋喃-2-基)苯硼酸频那醇酯合成路线 （共 4 条）
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; triethylamine in 1,4-dioxane
T=80°C;
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
1: hydrogenchloride; sodium nitrite / water / Cooling with ice
2: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; triethylamine / 1,4-dioxane / 80 °C
View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
1: 10 palladium on activated charcoal; hydrogen / ethanol
2: hydrogenchloride; sodium nitrite / water / Cooling with ice
3: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; triethylamine / 1,4-dioxane / 80 °C
View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene
2: 10 palladium on activated charcoal; hydrogen / ethanol
3: hydrogenchloride; sodium nitrite / water / Cooling with ice
4: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; triethylamine / 1,4-dioxane / 80 °C
View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
