2-二乙氨基氯乙烷盐酸盐合成路线 （共 91 条）
参考文献
Tilford et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1705,1707
反应条件
potassium carbonate; butanone
参考文献
Rohmann,C.; Meisel,D.
Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1961 , vol. 294, # 9 p. 538 - 549
反应条件
1: K2CO3; acetone
2: aqueous HCl
View Scheme
参考文献
Hager; Kramer
Journal of the American Pharmaceutical Association (1912-1977), 1955 , vol. 44, p. 649,652
反应条件
sodium hydroxide in water
T=20 - 55°C; 5.16 h;
参考文献
SANOFI; Grimaud, Bernard; Grossi, Pierre-Jean
Patent: US2014/18553 A1, 2014 ;
Location in patent: Paragraph 0273-0276 ;
反应条件
ethanol; sodium acetate
参考文献
King; Beer
Journal of the Chemical Society, 1945 , p. 791,792
反应条件
ethanol; sodium acetate
参考文献
Hoffmann-La Roche
Patent: US2626948 , 1950 ;
参考文献
Magidson; Gorbowizki
Chemische Berichte, 1935 , vol. 68, p. 656,658
Zhurnal Obshchei Khimii, 1935 , vol. 5, p. 1279,1282
参考文献
Protiva et al.
Cesko-Slovenska Farmacie, 1959 , vol. 8, p. 200,202
Chem.Abstr., 1960 , p. 6609
参考文献
Burtner; Cusic
Journal of the American Chemical Society, 1943 , vol. 65, p. 262,263
反应条件
sodium hydroxide in toluene
参考文献
Burke,H.M.; Joullie,M.M.
Journal of Medicinal Chemistry, 1978 , vol. 21, p. 1084 - 1086
