2-二乙氨基氯乙烷盐酸盐合成路线 （共 91 条）
反应条件
potassium carbonate in butanone
6 h; Reflux;
参考文献
Bansal, Ranju; Kumar, Gulshan; Gandhi, Deepika; Young, Louise C.; Harvey, Alan L.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 5 p. 2122 - 2127
反应条件
hydrogenchloride; potassium hydroxide
1.) H2O, toluene, 8 h, reflux, 2.) EtOH; Yield given. Multistep reaction;
参考文献
Vancurova; Krepelka; Smejkal
Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 7 p. 1867 - 1872
参考文献
Thuillier,G. et al.
Bulletin de la Societe Chimique de France, 1963 , p. 1087 - 1090
反应条件
triethylamine in N,N-dimethyl-formamide
2 h; Heating;
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
triethylamine in N,N-dimethyl-formamide
2 h; Heating;
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
(i) N2H4*H2O, (ii) K2CO3; Multistep reaction;
参考文献
Elslager,E.F. et al.
J. Med. Chem., 1964 , vol. 7, p. 493 - 500
参考文献
Kovalainen; Morimoto; Williams; Vepsalainen; Reijonen; Gynther
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 12 p. 1147 - 1156
反应条件
ethanol; sodium ethanolate
参考文献
Fourneau
Annales Pharmaceutiques Francaises, 1953 , vol. 11, p. 685,694
Full Text Show Details
Klosa
Pharmazie, 1955 , vol. 10, p. 62
反应条件
sodium hydroxide; potassium carbonate in anhydrous xylene; water
参考文献
Hoffmann-La Roche Inc.
Patent: US6150373 A1, 2000 ;
US 6150373 A
反应条件
copper; potassium carbonate; benzene
参考文献
Stahmann; Cope
Journal of the American Chemical Society, vol. 68>1946>2494
