T=110°C; 4 h;

1: 42 percent / ethanol / 17 h / Heating 2: 67 percent / 0.17 h / 100 °C 3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating 4: NBS / H2O; acetone 5: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C 6: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C 7: 53 percent / 4 h / 110 °C View Scheme

1: 67 percent / 0.17 h / 100 °C 2: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating 3: NBS / H2O; acetone 4: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C 5: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C 6: 53 percent / 4 h / 110 °C View Scheme

1: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C 2: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C 3: 53 percent / 4 h / 110 °C View Scheme

1: NBS / H2O; acetone 2: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C 3: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C 4: 53 percent / 4 h / 110 °C View Scheme

1: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating 2: NBS / H2O; acetone 3: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C 4: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C 5: 53 percent / 4 h / 110 °C View Scheme

1: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C 2: 53 percent / 4 h / 110 °C View Scheme

copper diacetate T=70°C; 1 h;

copper diacetate 1 h; Heating;