4-(2-氨基乙基)-1-苄基哌啶合成路线 （共 8 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 1880 - 1887
反应条件
1: 90.3 percent / CH2Cl2 / 20 °C 2: 85.5 percent / NaBH4; HCl 3: aq. NaOH 4: dimethylformamide / Heating 5: 83 percent / LiAlH4 / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 18 p. 4639 - 4642
反应条件
1: 74 percent / Mg / methanol / 4 h / Ambient temperature 2: 53 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 4 p. 730 - 741
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 0.25 h; Heating;
参考文献
Synthesis, , # 5 p. 388 - 389
反应条件
1: 85.5 percent / NaBH4; HCl 2: aq. NaOH 3: dimethylformamide / Heating 4: 83 percent / LiAlH4 / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 18 p. 4639 - 4642
反应条件
1: 61 percent / ethanol; H2O / 4.5 h / Heating 2: 52 percent / lithium aluminum hydride / tetrahydrofuran / 0.25 h / Heating View Scheme
参考文献
Synthesis, , # 5 p. 388 - 389
反应条件
1: aq. NaOH 2: dimethylformamide / Heating 3: 83 percent / LiAlH4 / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 18 p. 4639 - 4642
反应条件
1: 72.3 percent / tetrahydrofuran / 20 °C
2: 76.4 percent / CF3COOH / CH2Cl2 / 20 °C
View Scheme
参考文献
Shao, Dong; Zou, Chunyan; Luo, Cheng; Tang, Xican; Li, Yuanchao
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 18 p. 4639 - 4642
