sec.-butyllithium; (-)-sparteine 1.) Et2O, -78 deg C, 6 h, 2.) Et2O, from -78 deg C to RT; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Beak, Peter; Kerrick, Shawn T.; Wu, Shengde; Chu, Jingxi
Journal of the American Chemical Society, 1994 , vol. 116, # 8 p. 3231 - 3239
sec.-butyllithium; (-)-sparteine 1.) Et2O, -78 deg C, 6 h, 2.) Et2O, from -78 deg C to RT; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Beak, Peter; Kerrick, Shawn T.; Wu, Shengde; Chu, Jingxi
Journal of the American Chemical Society, 1994 , vol. 116, # 8 p. 3231 - 3239
1: N-Boc-pyrrolidine With sec.-butyllithium; (-)-sparteine in cyclohexane T=-78 - -68°C; 3 h; 2: With zinc(II) chloride in diethyl ether; cyclohexane T=-74 - 20°C; 3: bromobenzene With palladium diacetate; [(t-Bu)3PH]BF4 in diethyl ether; cyclohexane T=20°C; Negishi coupling; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 128, # 11 p. 3538 - 3539
