反应条件
1: 92 percent / Na, MeOH / 16 h / Heating 2: POCl3 / toluene / 1.5 h / Ambient temperature 3: sodium bis(2-methoxyethoxy)aluminum hydride / toluene / 1.5 h / 80 °C 4: 92.3 percent / H2 / 10percent Pd/C / methanol / 0.67 h / 760 Torr / Ambient temperature View Scheme
参考文献
Kierstead, R. W.; Faraone, A.; Mennona, F.; Mullin, J.; Guthrie, R. W.; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 11 p. 1561 - 1569
