6-甲氧基-2-苯基咪唑并[1,2-a]吡啶合成路线 （共 3 条）
反应条件
1,10-phenanthroline; caesium carbonate; copper(I) bromide
T=110°C; 24 h;
参考文献
El Kazzouli, Said; Griffon Du Bellay, Amaury; Berteina-Raboin, Sabine; Delagrange, Philippe; Caignard, Daniel-Henry; Guillaumet, Gerald
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4252 - 4257
反应条件
1: sodium hydrogencarbonate / ethanol / Reflux
2: 1,10-phenanthroline; caesium carbonate; copper(I) bromide / 24 h / 110 °C
View Scheme
参考文献
El Kazzouli, Said; Griffon Du Bellay, Amaury; Berteina-Raboin, Sabine; Delagrange, Philippe; Caignard, Daniel-Henry; Guillaumet, Gerald
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4252 - 4257
反应条件
1: copper / toluene / 1 h / Reflux
2: sodium tetrahydroborate / tetrahydrofuran; ethanol / Reflux
3: tetrachloromethane; sodium azide; triphenylphosphine / N,N-dimethyl-formamide / 6 h / 90 °C
4: palladium 10 on activated carbon; hydrogen / methanol / 20 °C
5: pyridine / dichloromethane / 3 h / 0 - 20 °C
View Scheme
参考文献
El Kazzouli, Said; Griffon Du Bellay, Amaury; Berteina-Raboin, Sabine; Delagrange, Philippe; Caignard, Daniel-Henry; Guillaumet, Gerald
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4252 - 4257
