O-去乙基坎地沙坦西来替昔酯合成路线 （共 5 条）
反应条件
methanol
24 h; Heating / reflux; Product distribution / selectivity;
参考文献
KRKA, D.D. NOVO MESTO
Patent: WO2007/42161 A1, 2007 ;
Location in patent: Page/Page column 16-17 ;
反应条件
hydrogenchloride; water in acetone
6 h; Reflux;
参考文献
Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav
Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362
反应条件
hydrogenchloride; water in acetone
6 h; Reflux;
参考文献
Havllcek, Jaroslav; Mandelova, Zuzana; Weisemann, Ruediger; Strelec, Ivo; Placek, Lukas; Radl, Stanislav
Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 2 p. 347 - 362
反应条件
in ethanol
T=50°C; 31 h; Product distribution / selectivity;
参考文献
TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.
Patent: WO2006/122254 A2, 2006 ;
Location in patent: Page/Page column 12; 13 ;
反应条件
T=55°C; 336 h; Product distribution / selectivity;
参考文献
TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.
Patent: WO2006/122254 A2, 2006 ;
Location in patent: Page/Page column 12; 13 ;
