7-氯-2,3-二甲基-庚酸甲酯合成路线 （共 5 条）
反应条件
potassium carbonate in acetone
T=20°C; 12 h;
参考文献
Calvet-Vitale, Sandrine; Vanucci-Bacque, Corinne; Fargeau-Bellassoued, Marie-Claude; Lhommet, Gerard
Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 2071 - 2077
反应条件
1-methyl-1H-imidazole; titanium tetrachloride; triphenylphosphine in dichloromethane
T=-50 - -45°C; Ti-crossed Claisen condensation;
参考文献
Iida, Akira; Nakazawa, Syogo; Nakatsuji, Hidefumi; Misaki, Tomonori; Tanabe, Yoo
Chemistry Letters, 2007 , vol. 36, # 1 p. 48 - 49
反应条件
hydrogenchloride in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Hannick; Kishi
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3833 - 3835
反应条件
1: 54 percent / zinc dust / tetrahydrofuran / 0.92 h / Heating
2: 84 percent / 10percent aq. HCl / tetrahydrofuran / 0.5 h / Ambient temperature
View Scheme
参考文献
Hannick; Kishi
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3833 - 3835
反应条件
hydrogenchloride; tetra-n-butylammonium tetrafluoroborate; zinc dibromide; zinc
1.) CH2Cl2, RT, 2.) CH2Cl2; Yield given. Multistep reaction;
参考文献
Zylber, N.; Zylber, J.; Rollin, Y.; Dunach, E.; Perichon, J.
Journal of Organometallic Chemistry, 1993 , vol. 444, # 1.2. p. 1 - 4
