(4-氟苄基)(吡啶-4-甲基)胺合成路线 (共 2 条)
反应条件
methanol; sodium cyanoborohydride
T=20°C; Molecular sieve;
参考文献
UNIVERSITETET I OSLO; TASKEN, Kjetil; LYGREN, Birgitte; ØSTENSEN, Ellen; KLAVENESS, Jo
Patent: WO2013/171332 A2, 2013 ;
Location in patent: Page/Page column 97; 98 ;
反应条件
1: tetrahydrofuran / 120 °C / 5171.62 Torr / solid phase reaction
2: sodium tetrahydroborate / methanol / 20 °C / Inert atmosphere; Cooling with ice
View Scheme
参考文献
Smith, Catherine J.; Smith, Christopher D.; Nikbin, Nikzad; Ley, Steven V.; Baxendale, Ian R.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 6 p. 1927 - 1937