乙氧基甲叉丙二酸二乙酯合成路线 （共 444 条）
反应条件
1: T=100°C; Gould-Jacobs reaction; 3 h; 2: in diphenylether T=250°C; Gould-Jacobs reaction; 2 h; Inert atmosphere;
参考文献
Li, Guo-Xiang; Liu, Zai-Qun; Luo, Xu-Yang
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1821 - 1827
反应条件
1: 93 percent / benzene / 8 h / Heating 2: 100 percent / Irradiation View Scheme
参考文献
Tetrahedron, , vol. 48, # 41 p. 9073 - 9084
反应条件
1: diphenylether / 8 h / 90 °C / Reflux 2: trichlorophosphate / 16 h / 90 °C View Scheme
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
反应条件
1: in Therminol VP1 T=248°C; 6.5 h; 2: With potassium hydroxide T=95 - 100°C; 9 h; 3: With sulfuric acid
参考文献
US6362340 B1, ;
Page column 8 ;
反应条件
1.) 110 deg C, 3 h, 2.) Ph2, Ph2O, 270 deg C; Multistep reaction;
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
反应条件
1: toluene / 4 h / Heating 2: diphenyl ether / 2 h / Heating View Scheme
参考文献
Bi, Yingzhi; Stoy, Patrick; Adam, Leonard; He, Bin; Krupinski, John; Normandin, Diane; Pongrac, Ron; Seliger, Laurie; Watson, Andrew; Macor, John E.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 6 p. 1577 - 1580
反应条件
1: 100 percent / 1 h / 90 - 110 °C 2: diphenyl ether / Heating View Scheme
参考文献
Conroy et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 3236
反应条件
1: T=120 - 150°C; 2: Heating;
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
反应条件
1: EtONa / ethanol 2: POCl3 View Scheme
参考文献
Lopes, Alexandra Basilio; Miguez, Eduardo; Kuemmerle, Arthur Eugen; Rumjanek, Victor Marcos; Fraga, Carlos Alberto Manssour; Barreiro, Eliezer J.
Molecules, 2013 , vol. 18, # 10 p. 11683 - 11704
反应条件
1: T=120 - 150°C; 2: Heating;
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
