乙氧基甲叉丙二酸二乙酯合成路线

参考文献

Reis, Raisa Da R.; Azevedo, Elisa C.; De Souza, Maria Cecilia B.V.; Ferreira, Vitor Francisco; Montenegro, Raquel C.; Araujo, Ana Jersia; Pessoa, Claudia; Costa-Lotufo, Leticia V.; De Moraes, Manoel O.; Filho, Jose D.B.M.; De Souza, Alessandra M.T.; De Carvalho, Natasha C.; Castro, Helena C.; Rodrigues, Carlos R.; Vasconcelos, Thatyana R.A.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1448 - 1452

104-94-9对甲氧基苯胺+

87-13-8乙氧基甲叉丙二酸二乙酯

22931-71-14-氯-6-甲氧基喹啉-3-甲酸乙酯

参考文献

Goncalves, Victor; Brannigan, James A.; Whalley, David; Ansell, Keith H.; Saxty, Barbara; Holder, Anthony A.; Wilkinson, Anthony J.; Tate, Edward W.; Leatherbarrow, Robin J.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3578 - 3582

455-14-1对三氟甲基苯胺+

87-13-8乙氧基甲叉丙二酸二乙酯

175203-85-74-羟基-6-(三氟甲氧基)喹啉-3-羧酸乙酯

参考文献

Pharmacia and Upjohn Company
Patent: US6093732 A1, 2000 ;

87-13-8乙氧基甲叉丙二酸二乙酯

175203-85-74-羟基-6-(三氟甲氧基)喹啉-3-羧酸乙酯

参考文献

Savini; Massarelli; Nencini; Pellerano; Biggio; Maciocco; Tuligi; Carrieri; Cinone; Carotti
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 4 p. 389 - 399

554-00-72,4-二氯苯胺+

87-13-8乙氧基甲叉丙二酸二乙酯

25771-89-56,8-二氯-4-羟基喹啉-3-羧酸乙酯

参考文献

Li, Guo-Xiang; Liu, Zai-Qun; Luo, Xu-Yang
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1821 - 1827

87-13-8乙氧基甲叉丙二酸二乙酯

2134-36-34-氯-2-甲基嘧啶-5-甲酸乙酯

参考文献

Scott, James S.; Gill, Adrian L.; Godfrey, Linda; Groombridge, Sam D.; Rees, Amanda; Revill, John; Schofield, Paul; Soerme, Pernilla; Stocker, Andrew; Swales, John G.; Whittamore, Paul R.O.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6756 - 6761

74497-02-2+

87-13-8乙氧基甲叉丙二酸二乙酯

26892-90-04-羟基喹啉-3-甲酸乙酯

参考文献

AVANIR PHARMACEUTICALS
Patent: WO2005/123686 A1, 2005 ;
Location in patent: Page/Page column 75-76 ;
WO 2005/123686 A1

87-13-8乙氧基甲叉丙二酸二乙酯

26892-90-04-羟基喹啉-3-甲酸乙酯

参考文献

Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;

17238-53-8哌啶-1-甲脒硫酸盐+

87-13-8乙氧基甲叉丙二酸二乙酯

25693-43-04-羟基-2-(哌啶-1-基)嘧啶-5-羧酸乙酯

参考文献

Sirakawa
Yakugaku Zasshi, 1959 , vol. 79, p. 1487,1491
Chem.Abstr., 1960 , p. 11039

87-13-8乙氧基甲叉丙二酸二乙酯

25693-43-04-羟基-2-(哌啶-1-基)嘧啶-5-羧酸乙酯

参考文献

Sirakawa
Yakugaku Zasshi, 1959 , vol. 79, p. 1487,1491
Chem.Abstr., 1960 , p. 11039