乙氧基甲叉丙二酸二乙酯合成路线 （共 444 条）
参考文献
Osawa; Tatsushi; Ohta; Hideo; Akimoto; Kohji; Harada; Katsuhiko; Soga; Hiroshi; Jinno; Yasuhiro
Patent: US5081121 A1, 1992 ;
反应条件
1: 2 h / 110 - 115 °C 2: various solvent(s) / 0.5 h / 250 °C 3: POCl3 / 5 h / Heating View Scheme
参考文献
Farmaco, , vol. 53, # 8-9 p. 579 - 585
反应条件
Multistep reaction.;
参考文献
Takamura; Funabashi; Kanai; Shibasaki
Journal of the American Chemical Society, 2001 , vol. 123, # 28 p. 6801 - 6808
反应条件
1: in Therminol VP1 T=248°C; 6.5 h; 2: With potassium hydroxide T=95 - 100°C; 9 h; 3: With sulfuric acid
参考文献
US6362340 B1, ;
Page column 8 ;
参考文献
SCHERING AKTIENGESELLSCHAFT
Patent: WO2004/113323 A1, 2004 ;
Location in patent: Page 30; 31 ;
WO 2004/113323 A1
参考文献
Gerphagnon et al.
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1958 , vol. 246, p. 1701
参考文献
Kumiai Chemical Industry Co., Ltd.; Ihara Chemical Industry Co., Ltd.
Patent: US4742063 A1, 1988 ;
反应条件
1: 89 percent / 1 h / 120 °C 2: 77 percent / POCl3 / 18 h / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 15 p. 4089 - 4100
反应条件
1: T=160°C; 5 h; 2: With thionyl chloride
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 7 p. 2340 - 2343
参考文献
Santilli,A.A. et al.
Journal of Medicinal Chemistry, 1964 , vol. 7, p. 68 - 72
