乙氧基甲叉丙二酸二乙酯合成路线

参考文献

Elworthy, Todd R.; Ford, Anthony P. D. W.; Bantle, Gary W.; Morgans Jr., David J.; Ozer, Rachel S.; Palmer, Wylie S.; Repke, David B.; Romero, Magarita; Sandoval, Leticia; Sjogren, Eric B.; Talamas, Francisco X.; Vazquez, Alfredo; Wu, Helen; Arredondo, Nicolas F.; Blue Jr., David R.; DeSousa, Andrea; Gross, Lisa M.; Kava, M. Shannon; Lesnick, John D.; Vimont, Rachel L.; Williams, Timothy J.; Zhu, Quan-Ming; Pfister, Juerg R.; Clarke, David E.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 17 p. 2674 - 2687

1192-21-81-甲基-5-氨基吡唑+

87-13-8乙氧基甲叉丙二酸二乙酯

37801-57-34-氯-1-甲基-1H-吡唑并[3,4-b]吡啶-5-羧酸乙酯

参考文献

Rimland, Joseph; Dunne, Angela; Hunjan, Suchete S.; Sasse, Rosemary; Uings, Iain; Montanari, Dino; Caivano, Matilde; Shah, Poonam; Standing, David; Gray, David; Brown, David; Cairns, William; Trump, Ryan; Smith, Paul W.; Bertheleme, Nicolas; D'Alessandro, Pier; Gul, Sheraz; Vimal, Mythily; Smith, David N.; Watson, Stephen P.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 7 p. 2340 - 2343

87-13-8乙氧基甲叉丙二酸二乙酯

37801-57-34-氯-1-甲基-1H-吡唑并[3,4-b]吡啶-5-羧酸乙酯

参考文献

Ochiai, Hiroshi; Ishida, Akiharu; Ohtani, Tazumi; Kusumi, Kensuke; Kishikawa, Katuya; Yamamoto, Susumu; Takeda, Hiroshi; Obata, Takaaki; Nakai, Hisao; Toda, Masaaki
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 9 p. 1098 - 1104

1779-81-32-氨基-2-噻唑啉+

87-13-8乙氧基甲叉丙二酸二乙酯

32084-53-05-氧代-2,3-二氢-5H-[1,3]噻唑并-[3,2-a]嘧啶-6-羧酸乙酯

参考文献

Shridhar, D. R.; Jogibhukta, M.; Joshi, P. P.; Rao, C. Seshagiri; Junnarkar, A. Y.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 5 p. 492 - 494

635-46-11,2,3,4-四氢喹啉

42835-54-11-氧代-6,7-二氢-1H,5H-吡啶并[3,2,1-ij]喹啉-2-羧酸

参考文献

Otsuka Pharmaceutical Co., Ltd.
Patent: US4317820 A1, 1982 ;

74497-02-2+

87-13-8乙氧基甲叉丙二酸二乙酯

52980-28-61,4-二氢-4-氧代-3-喹啉羧酸乙酯

参考文献

Osornio, Yazmin M.; Miranda, Luis D.; Cruz-Almanza, Raymundo; Muchowski, Joseph M.
Tetrahedron Letters, 2004 , vol. 45, # 13 p. 2855 - 2858

87-13-8乙氧基甲叉丙二酸二乙酯

52980-28-61,4-二氢-4-氧代-3-喹啉羧酸乙酯

参考文献

Srivastava, Nivedita; Kumar, Anil
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 464 - 468

23255-20-13-吡啶甲脒+

87-13-8乙氧基甲叉丙二酸二乙酯

34750-63-51,6-二氢-6-氧代-2-(3-吡啶)-5-嘧啶羧酸乙酯

参考文献

COATS, STEVEN J.; BIAN, HAIYAN; CONNOLLY, PETER J.; BIGNAN, GILLES; CAI, CHAOZHONG; DAX, SCOTT L.; DECORTE, BART L.; LIN, SHU-CHEN; LIU, LI; MACIELAG, MARK J.; PITIS, PHILIP M.; ZHANG, YUE-MEI; ZHU, BIN; HE, WEI
Patent: US2011/105520 A1, 2011 ;
Location in patent: Page/Page column 44-45 ;

504-29-02-氨基吡啶+

87-13-8乙氧基甲叉丙二酸二乙酯

32092-18-54-氧代-4H-吡啶并[1,2-a]嘧啶-3-羧酸乙酯

参考文献

Hajimahdi; Zarghi; Zabihollahi; Aghasadeghi
Medicinal Chemistry Research, 2013 , vol. 22, # 5 p. 2467 - 2475

87-13-8乙氧基甲叉丙二酸二乙酯

692764-07-1

参考文献

Pasquini, Serena; De Rosa, Maria; Pedani, Valentina; Mugnaini, Claudia; Guida, Francesca; Luongo, Livio; De Chiaro, Maria; Maione, Sabatino; Dragoni, Stefania; Frosini, Maria; Ligresti, Alessia; Di Marzo, Vincenzo; Corelli, Federico
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5444 - 5453