乙氧基甲叉丙二酸二乙酯合成路线 （共 444 条）
反应条件
sodium acetate in ethanol
12 h; Heating;
参考文献
Donkor, Augustine; Prager, Rolf H.; Thompson, Malcolm J.
Australian Journal of Chemistry, 1992 , vol. 45, # 10 p. 1571 - 1576
反应条件
in ethanol
T=120°C; 6 h; Heating / reflux;
参考文献
YUNGJIN PHARMACEUTICAL CO., LTD.
Patent: WO2008/93940 A1, 2008 ;
Location in patent: Page/Page column 88-90 ;
WO 2008/093940 A1
参考文献
Zeneca Limited
Patent: US6200974 B1, 2001 ;
参考文献
Pharmacia and Upjohn Company LLC
Patent: EP1042295 B1, 2005 ;
Location in patent: Page/Page column 59 ;
反应条件
in various solvent(s)
5 h; Heating;
参考文献
Sahu, J. K.; Nayak, A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 654 - 655
反应条件
1: 0.75 h / 110 - 120 °C
2: 20 percent / PPA / 4 h / 110 °C
View Scheme
参考文献
Sahu, J. K.; Nayak, A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 654 - 655
参考文献
Whitehead; Traverso
Journal of the American Chemical Society, 1956 , vol. 78, p. 5294,5296
参考文献
Whitehead; Traverso
Journal of the American Chemical Society, 1956 , vol. 78, p. 5294,5296
参考文献
Gupte; Sunthankar
Journal of Organic Chemistry, 1959 , vol. 24, p. 1334
反应条件
(i) Mg, Et2O, (ii) /BRN= 880058/; Multistep reaction;
参考文献
Nabar,D.P.; Sunthankar,S.V.
Bulletin of the Chemical Society of Japan, 1969 , vol. 42, p. 2991 - 2993
