乙氧基甲叉丙二酸二乙酯合成路线 （共 444 条）
参考文献
Gupta, K. A.; Saxena, Anil K.; Jain, Padam C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 3 p. 228 - 233
参考文献
Gupta, K. A.; Saxena, Anil K.; Jain, Padam C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 3 p. 228 - 233
参考文献
Gupta, K. A.; Saxena, Anil K.; Jain, Padam C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 3 p. 228 - 233
反应条件
T=14 - 95°C; 2.91667 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2006/2047 A2, 2006 ;
Location in patent: Page/Page column 60 ;
反应条件
1: 59 percent / 10 h / 90 °C / excess of diethyl ethoxymethylenemalonate
2: diphenyl ether / 0.33 h / 250 °C
View Scheme
参考文献
Hirose; Mishio; Matsumoto; Minami
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 7 p. 2399 - 2409
参考文献
Osawa; Tatsushi; Ohta; Hideo; Akimoto; Kohji; Harada; Katsuhiko; Soga; Hiroshi; Jinno; Yasuhiro
Patent: US5081121 A1, 1992 ;
反应条件
1: 100 percent / 2 h / 130 °C
2: 37 percent / diphenyl ether / 1 h / Heating
View Scheme
参考文献
Lager, Erik; Andersson, Pierre; Nilsson, Jakob; Pettersson, Ingrid; Nielsen, Elsebet stergaard; Nielsen, Mogens; Sterner, Olov; Liljefors, Tommy
Journal of Medicinal Chemistry, 2006 , vol. 49, # 8 p. 2526 - 2533
反应条件
in ethanol
1.5 h; Heating;
参考文献
Markees, Diether G.
Helvetica Chimica Acta, 1983 , vol. 66, # 2 p. 620 - 626
反应条件
1: 75 percent / ethanol / 1.5 h / Heating
2: 86 percent / diphenyl ether / Heating
3: K2CO3 / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Markees, Diether G.
Helvetica Chimica Acta, 1983 , vol. 66, # 2 p. 620 - 626
反应条件
2: diphenyl ether
View Scheme
参考文献
Banerji, Biswadip; Conejo-Garcia, Ana; McNeill, Luke A.; McDonough, Michael A.; Buck, Matthew R. G.; Hewitson, Kirsty S.; Oldham, Neil J.; Schofield, Christopher J.
Chemical Communications, 2005 , # 43 p. 5438 - 5440
