反应条件
1.1: hydrogenchloride / 1-methyl-pyrrolidin-2-one; water / 13 h / 90 °C / Inert atmosphere 2.1: 1,3-dibromo-5,5-dimethyl-hydantoin / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 1 - 6 °C / Inert atmosphere; Darkness 3.1: isopropylmagnesium chloride lithium chloride complex / tetrahydrofuran / 2 - 4 h / 9 - 23 °C / Inert atmosphere 3.2: 3 - 4 h / 2 - 23 °C / Inert atmosphere View Scheme
参考文献
Thieu, Tho; Sclafani, Joseph A.; Levy, Daniel V.; McLean, Andrew; Breslin, Henry J.; Ott, Gregory R.; Bakale, Roger P.; Dorsey, Bruce D.
Organic Letters, 2011 , vol. 13, # 16 p. 4204 - 4207
