1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
2: 100 percent / NaH 3: 80 percent / nickel(II) bisacetylacetonate 4: 90 percent / stannic chloride / CH2Cl2 / 0 °C 5: stannic chloride / CH2Cl2 View Scheme
参考文献
Armstrong, Rosemary J.; Harris, Francis L.; Weiler, Larry
Canadian Journal of Chemistry, 1982 , vol. 60, p. 673 - 675
反应条件
1: 69 percent / K2CO3 / acetone 2: 53 percent / 1 N HCl (aq.) / ethanol / 1 h / 60 °C View Scheme
参考文献
Nakagawa, Masako; Matsuki, Kenji; Hino, Tohru
Tetrahedron Letters, 1983 , vol. 24, # 21 p. 2171 - 2174
反应条件
potassium hydroxide in methanol T=20°C; 24 h;
参考文献
Wang, Xue; Lee, Yong Rok
Tetrahedron, 2011 , vol. 67, # 47 p. 9179 - 9184
反应条件
potassium carbonate in acetone T=74°C; 4 h;
参考文献
Basabe; De Roman; Marcos; Diez; Blanco; Bodero; Mollinedo; Sierra; Urones
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 9 p. 4258 - 4269
参考文献
Riedl; Huebner
Chemische Berichte, 1957 , vol. 90, p. 2870,2875
反应条件
1.1: NaH / toluene / 0.17 h / 0 °C 1.2: 55 percent / toluene / 12 h / 35 °C 2.1: polystyrene-based selenenyl bromide resin / CH2Cl2 / 0.33 h / 0 - 25 °C 2.2: H2O2 / tetrahydrofuran / 0.33 h / 25 °C View Scheme
参考文献
Nicolaou; Pfefferkorn; Roecker; Cao; Barluenga; Mitchell
Journal of the American Chemical Society, 2000 , vol. 122, # 41 p. 9939 - 9953
反应条件
potassium carbonate in acetone 8 h; Reflux;
参考文献
Vijaya Bhaskar Reddy; Tsai, Wei-Jern; Qian, Keduo; Lee, Kuo-Hsiung; Wu, Tian-Shung
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 24 p. 7711 - 7719
反应条件
potassium hydroxide in water T=0 - 25°C; Alkylation; 13 h;
参考文献
Tan, Wenfei; Li, Wei-Dong Z.; Huang, Chusheng; Li, Yulin; Xing, Yacheng
Synthetic Communications, 1999 , vol. 29, # 19 p. 3369 - 3377
反应条件
potassium hydroxide in water T=20°C; Inert atmosphere;
参考文献
Grealis, John P.; Mueller-Bunz, Helge; Ortin, Yannick; Casey, Michael; McGlinchey, Michael J.
European Journal of Organic Chemistry, 2013 , # 2 p. 332 - 347
反应条件
benzoylchlorobis(triphenylphosphine)palladium(II) in benzene T=100°C; 24 h;
参考文献
Godschalx, James; Stille, J. K.
Tetrahedron Letters, 1980 , vol. 21, p. 2599 - 2602
