1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
sodium carbonate; potassium iodide in N,N-dimethyl-formamide 22.5 h; Ambient temperature;
参考文献
Kukla, Michael J.; Breslin, Henry J.; Pauwels, Rudi; Fedde, Cynthia L.; Miranda, Milton; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 746 - 751
反应条件
1: 24 percent / KOH / H2O / 24 h / Ambient temperature 2: 92 percent / K2CO3 / acetone / 3 h / Heating 3: 89 percent / KOH / ethanol; H2O / Ambient temperature 4: 80 percent / NaOAc / ethanol; H2O / 24 h / Heating 5: 92 percent / 3 N aq. HCl / methanol / 0.25 h / Heating View Scheme
参考文献
Zhao, Lianyun; Li, Yulin
Organic Preparations and Procedures International, 1996 , vol. 28, # 2 p. 165 - 171
反应条件
1: CH(CH2CH=CH2)(CO2Me)2 With sodium hydride in tetrahydrofuran T=23°C; 1 h; 2: prenyl bromide in tetrahydrofuran T=23°C;
参考文献
Kerber, William D.; Gagne, Michel R.
Organic Letters, 2005 , vol. 7, # 15 p. 3379 - 3381
反应条件
1: 1) n-BuLi / 1) diethyl ether, 1 h, reflux, 2) 1 h, 40 deg C 2: 34.4 percent / EtSNa / dimethylformamide / 3 h / 170 - 180 °C View Scheme
参考文献
Asakawa, Yoshinori; Kondo, Keiko; Tori, Motoo; Hashimoto, Toshihiro; Ogawa, Shunichi
Phytochemistry (Elsevier), 1991 , vol. 30, # 1 p. 219 - 234
反应条件
sodium methylate 1) methanol, room temp., 30 min, 2) benzene, 50-55 deg C, 30 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Asakawa, Yoshinori; Kondo, Keiko; Tori, Motoo; Hashimoto, Toshihiro; Ogawa, Shunichi
Phytochemistry (Elsevier), 1991 , vol. 30, # 1 p. 219 - 234
反应条件
potassium carbonate; lithium iodide in butanone 18 h; Heating;
参考文献
Rutjes; Hiemstra; Pirrung; Speckamp
Tetrahedron, 1993 , vol. 49, # 44 p. 10027 - 10048
反应条件
1: 2 percent / K2CO3 / methanol / 3 h / Ambient temperature 2: 30 percent / Dowex 50 / methanol / 10 h / 55 °C View Scheme
参考文献
Fukai, Toshio; Nomura, Taro
Heterocycles, 1992 , vol. 34, # 6 p. 1213 - 1225
反应条件
1: aqueous KOH 2: platinum; methanol / Hydrogenation View Scheme
参考文献
Nickl
Chemische Berichte, 1958 , vol. 91, p. 553,563
反应条件
1: 70 percent / Bu4NI / dimethylformamide / 2 h / 70 °C 2: 35 percent / NaOH, Bu4NI / dimethylformamide / 1200 h / -10 - 20 °C / other PT-catalysts, bases, temperatures, times and catalyst/reactant ratios View Scheme
参考文献
Hanack, Michael; Auchter, Anneliese; Wunde, Christian; Stoll, Theodor
Liebigs Annalen der Chemie, 1989 , p. 853 - 858
反应条件
sodium hydride 1. DMF, 80 deg C, 1 h; 2. 100 deg C, 12 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Holy, Antonin
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 1 p. 248 - 265
