1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Guller; Dobler; Borschberg
Helvetica Chimica Acta, 1991 , vol. 74, # 8 p. 1636 - 1642
反应条件
1: 4-hydroxyiodobenzene With sodium in diethyl ether T=0°C; 3 h; 2: prenyl bromide in diethyl ether T=25°C; 8 h;
参考文献
Lykakis, Ioannis N.; Efe, Christina; Gryparis, Charis; Stratakis, Manolis
European Journal of Organic Chemistry, 2011 , # 12 p. 2334 - 2338
反应条件
10percent NaOH T=20°C; 5 h;
参考文献
Uto, Yoshihiro; Hirata, Akihiko; Fujita, Tomoya; Takubo, Syunsuke; Nagasawa, Hideko; Hori, Hitoshi
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 2355 - 2357
反应条件
decacarbonyldimanganese (2) in dichloromethane Radical coupling; UV-irradiation; Title compound not separated from byproducts;
参考文献
Gilbert, Bruce C.; Lindsay, Chris I.; McGrail, P. Terry; Parsons, Andrew F.; Whittaker, David T.E.
Synthetic Communications, 1999 , vol. 29, # 15 p. 2711 - 2718
反应条件
1.1: NaH / tetrahydrofuran / 0.17 h / 0 °C 1.2: n-BuLi / tetrahydrofuran; hexane / 0.33 h / 0 °C 1.3: tetrahydrofuran; hexane / 0.5 h / 0 - 20 °C 2.1: methanesulfonyl azide; triethylamine / acetonitrile / 4 h / 20 °C 3.1: aqueous NaOH / 0.5 h View Scheme
参考文献
Saha, Biswajit; Uchida, Tatsuya; Katsuki, Tsutomu
Tetrahedron Asymmetry, 2003 , vol. 14, # 7 p. 823 - 836
反应条件
1: NaOMe / methanol 2: formic acid View Scheme
参考文献
Barua, P.; Barua, N. C.; Sharma, R.P.
Tetrahedron Letters, 1983 , vol. 24, # 51 p. 5801 - 5804
反应条件
potassium hydroxide in water T=0°C;
参考文献
Crombie; Jones; Palmer
Tetrahedron Letters, 1985 , vol. 26, # 24 p. 2929 - 2932
反应条件
sodium methylate in methanol
参考文献
Barua, P.; Barua, N. C.; Sharma, R.P.
Tetrahedron Letters, 1983 , vol. 24, # 51 p. 5801 - 5804
反应条件
1: 4-bromo-phenol With sodium in diethyl ether Metallation; 2: prenyl bromide With zinc dibromide in dichloromethane Alkylation;
参考文献
Li, Yuan-Qiang; Sugase, Kenji; Ishiguro, Masaji
Tetrahedron Letters, 1999 , vol. 40, # 51 p. 9097 - 9100
反应条件
sodium carbonate; potassium iodide in N,N-dimethyl-formamide 22.5 h; Ambient temperature;
参考文献
Kukla, Michael J.; Breslin, Henry J.; Pauwels, Rudi; Fedde, Cynthia L.; Miranda, Milton; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 2 p. 746 - 751
