1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
hexamethyl-distannane in benzene
T=25°C; 5 h; Irradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Yanagisawa, Akira; Noritake, Yoshiyuki; Yamamoto, Hisashi
Chemistry Letters, 1988 , p. 1899 - 1902
反应条件
1: 1) BuLi / 1) cyclohexane, reflux, 2 h, 2) Et2O, reflux, 2 h
2: 5percent aq. oxalic acid / methanol / Ambient temperature
View Scheme
参考文献
Gulacsi, Katalin; Litkei, Gyoergy; Antus, Sandor; Szantay, Csaba; Darko, Laszlo L.; Szelenyi, Judith; Hasko, Gyoergy; Vizi, Szilveszter E.
Archiv der Pharmazie, 2001 , vol. 334, # 2 p. 53 - 61
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=0 - 20°C; Alkylation;
参考文献
Breslin, Henry J.; Kukla, Michael J.; Kromis, Teresa; Cullis, Heather; De Knaep, Fons; Pauwels, Rudi; Andries, Koen; De Clercq, Erik; Janssen, Marcel A.C.; Janssen, Paul A.J.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 11 p. 2427 - 2436
反应条件
1: 76 percent / n-butyllithium, diisopropylamine, HMPT / tetrahydrofuran; hexane / 0 °C
2: 98 percent / 450 °C / 0.01 Torr
View Scheme
参考文献
Bloch, R.
Tetrahedron, 1983 , vol. 39, # 4 p. 639 - 644
反应条件
potassium hydroxide in water
T=20°C; Inert atmosphere;
参考文献
Grealis, John P.; Mueller-Bunz, Helge; Ortin, Yannick; Casey, Michael; McGlinchey, Michael J.
European Journal of Organic Chemistry, 2013 , # 2 p. 332 - 347
反应条件
Montmorillonite K10 clay in tetrachloromethane
2 h;
参考文献
Dintzner, Matthew R.; McClelland, Kristen M.; Morse, Kara M.; Akroush, Michael H.
Synlett, 2004 , # 11 p. 2028 - 2030
反应条件
copper(I) bromide in dichloromethane
T=20°C; 24 h; Yield given. Yields of byproduct given;
参考文献
Badet, B.; Julia, M.; Ramirez-Munoz, M.; Sarrazin, C. A.
Tetrahedron, 1983 , vol. 39, # 19 p. 3111 - 3126
反应条件
sodium methylate in methanol
参考文献
Barua, P.; Barua, N. C.; Sharma, R.P.
Tetrahedron Letters, 1983 , vol. 24, # 51 p. 5801 - 5804
反应条件
sodium acetate; acetic acid
参考文献
Pochini,A. et al.
Gazzetta Chimica Italiana, 1975 , vol. 105, p. 1245 - 1252
反应条件
2: (i) nBuLi, (ii) /BRN= 2321514/
3: (i) Li, EtNH2, (ii) aq. FeCl3, AcOH
View Scheme
参考文献
Terao,S. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1978 , p. 1101 - 1110
