反应条件
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 - -65 °C / |Inert atmosphere
1.2: 0.03 h / -78 - -70 °C
2.1: phosphoric acid / toluene / 7 h
3.1: 12 h / -20 - 20 °C / |Large scale
4.1: 1,1'-carbonyldiimidazole / ethyl acetate / 2 h / 20 - 60 °C / |Large scale
4.2: 4 h / 20 °C / |Large scale
View Scheme
参考文献
Li, Bryan; Andresen, Brian; Brown, Matthew F.; Buzon, Richard A.; Chiu, Charles K.-F.; Couturier, Michel; Dias, Eric; Urban, Frank J.; Jasys, V. John; Kath, John C.; Kissel, William; Le, Tung; Li, Z. Jane; Negri, Joanna; Poss, Christopher S.; Tucker, John; Whritenour, David; Zandi, Kathleen
Organic Process Research and Development, 2005 , vol. 9, # 4 p. 466 - 471
