1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
1: 85 percent / NaOEt / ethanol / 1 h / Heating
2: 99 percent Spectr. / Et3Al / NiBr2(PPh3)2 / toluene / 24 h / 20 °C
View Scheme
参考文献
Necas, David; Tursky, Matyas; Kotora, Martin
Journal of the American Chemical Society, 2004 , vol. 126, # 33 p. 10222 - 10223
参考文献
Staudinger; Kreis; Schilt
Helvetica Chimica Acta, 1922 , vol. 5, p. 750
反应条件
in terms of solvents, catalysts, reagents, and temperature; Product distribution;
参考文献
Cuvigny, Therese; Julia, Marc
Journal of Organometallic Chemistry, 1987 , vol. 331, # 1 p. 121 - 138
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in toluene
T=50°C; 4 h; Further byproducts given;
参考文献
Reisch; Mueller; Mester
1981 , vol. 36, # 9 p. 1176 - 1179
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in toluene
T=50°C; 4 h; Further byproducts given;
参考文献
Reisch; Mueller; Mester
1981 , vol. 36, # 9 p. 1176 - 1179
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in toluene
T=50°C; 4 h; Product distribution;
参考文献
Reisch; Mueller; Mester
1981 , vol. 36, # 9 p. 1176 - 1179
反应条件
potassium carbonate in acetone
Heating;
参考文献
Grundon, Michael F.; Ramachandran, V. N.
Tetrahedron Letters, 1985 , vol. 26, # 35 p. 4253 - 4256
反应条件
1.1: n-BuLi / tetrahydrofuran / 0.5 h / -78 °C
1.2: CuI / tetrahydrofuran / 1.5 h / -78 - 20 °C
2.1: conc. HCl / CHCl3; methanol / 1 h / Heating
3.1: MnO2 / benzene / 0.5 h / 20 °C
4.1: pyridine / 4 h / Heating
5.1: H2 / PtO2 / ethyl acetate / 2 h / 20 °C
View Scheme
参考文献
Terashima, Kenji; Takaya, Yoshiaki; Niwa, Masatake
Bioorganic and medicinal chemistry, 2002 , vol. 10, # 5 p. 1619 - 1625
反应条件
potassium hydroxide in water
T=0 - 25°C; Alkylation; 13 h;
参考文献
Tan, Wenfei; Li, Wei-Dong Z.; Huang, Chusheng; Li, Yulin; Xing, Yacheng
Synthetic Communications, 1999 , vol. 29, # 19 p. 3369 - 3377
反应条件
potassium hydroxide in water
T=20°C; Inert atmosphere;
参考文献
Grealis, John P.; Mueller-Bunz, Helge; Ortin, Yannick; Casey, Michael; McGlinchey, Michael J.
European Journal of Organic Chemistry, 2013 , # 2 p. 332 - 347
