1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
参考文献
Nishiyama, Kozaburo; Karigomi, Hiroshi
Chemistry Letters, 1982 , p. 1477 - 1478
反应条件
n-butyllithium; ammonium chloride; diisopropylamine in tetrahydrofuran
参考文献
Smets, Johan; Denutte, Hugo Robert Germain; Pintens, An; Van Aken, Koen; Vrielynck, Freek Annie Camiel
Patent: US2011/308556 A1, 2011 ;
反应条件
3: 80 percent / diethyl ether; tetrahydrofuran / 24 h / Ambient temperature
4: 80 percent / HCl, MeOH / CH2Cl2 / 0.02 h / Ambient temperature
5: 70 percent / H2O2, H2O, KF, KHCO3 / tetrahydrofuran; methanol / 0.33 h / Ambient temperature
View Scheme
参考文献
Fleming, Ian; Lee, Duckhee
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2701 - 2709
反应条件
n-butyllithium in hexane
96 h; Heating;
参考文献
Paulini, Klaus; Reissig, Hans-Ulrich
Liebigs Annalen der Chemie, 1991 , # 5 p. 455 - 461
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hahn, Gregory; Zweifel, George
Synthesis, 1983 , # 11 p. 883 - 885
反应条件
Yield given. Multistep reaction;
参考文献
Hahn, Gregory; Zweifel, George
Synthesis, 1983 , # 11 p. 883 - 885
反应条件
1: 79 percent / NaH, n-BuLi / tetrahydrofuran / 0 °C
2: p-TsOH / benzene / Heating
View Scheme
参考文献
Funakoshi, Kazuhisa; Togo, Nagako; Taura, Yukari; Sakai, Kiyoshi
Chemical & Pharmaceutical Bulletin, 1989 , vol. 37, # 7 p. 1776 - 1779
反应条件
1: 79 percent / NaH, n-BuLi / tetrahydrofuran / 0 °C
2: p-TsOH / benzene / Heating
3: LiAlH4 / diethyl ether
4: CBr4, PPh3 / benzene / 0.5 h / Heating
View Scheme
参考文献
Urano, Shiro; Tokuzawa, Kumiko; Nakano, Shun-Ichiro; Matsuo, Mitsuyoshi
Heterocycles, 1984 , vol. 22, # 2 p. 257 - 260
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; indium; triphenylphosphine; lithium chloride in N,N-dimethyl-formamide
T=100°C; 8 h; Inert atmosphere;
参考文献
Lee, Kooyeon; Kim, Hyunseok; Mo, Juntae; Lee, Phil Ho
Chemistry - An Asian Journal, 2011 , vol. 6, # 8 p. 2147 - 2157
反应条件
sodium amide in diethyl ether
3 h; Heating;
参考文献
Frejd, Torbjoern; Karlsson, J. Olle
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1983 , vol. 37, # 10 p. 895 - 900
