1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate in toluene
T=110°C; Suzuki-Miyaura coupling; 17 h; Inert atmosphere;
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
1: 4,4,5,5-tetramethyl-2-phenyl-[1,3,2]-dioxaborolane With sec.-butyllithium in tetrahydrofuran; hexane
T=-78 - 20°C; Suzuki-Miyaura coupling; Inert atmosphere;
2: prenyl bromide With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in tetrahydrofuran; hexane
Suzuki-Miyaura coupling; Inert atmosphereReflux;
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
palladium diacetate in 1,4-dioxane
T=100°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Gerbino, Dario C.; Mandolesi, Sandra D.; Schmalz, Hans-Guenther; Podesta, Julio C.
European Journal of Organic Chemistry, 2009 , # 23 p. 3964 - 3972
反应条件
water; palladium diacetate; potassium carbonate in toluene
T=90°C; 3 h;
参考文献
Scrivanti, Alberto; Beghetto, Valentina; Bertoldini, Matteo; Matteoli, Ugo
European Journal of Organic Chemistry, 2012 , # 2 p. 264 - 268
反应条件
water; palladium diacetate; potassium carbonate in toluene
T=90°C; 3 h;
参考文献
Scrivanti, Alberto; Beghetto, Valentina; Bertoldini, Matteo; Matteoli, Ugo
European Journal of Organic Chemistry, 2012 , # 2 p. 264 - 268
反应条件
copper(l) iodide; boron trifluoride diethyl etherate in diethyl ether
other Lewis acids, solvents; Product distribution;
参考文献
Yamamoto, Yoshinori; Yamamoto, Shinichi; Yatagai, Hidetaka; Maruyama, Kazuhiro
Journal of the American Chemical Society, 1980 , vol. 102, # 7 p. 2318 - 2325
反应条件
(i) Ni(CO)4, benzene, (ii) /BRN= 1446140/, DMF; Multistep reaction;
参考文献
Sato; Inoue; Yamaguchi
The Journal of organic chemistry, 1972 , vol. 37, # 12 p. 1889 - 1892
反应条件
folgend Behandlung des Reaktionsprodukts mit verd. Salzsaeure;
参考文献
Staudinger; Kreis; Schilt
Helvetica Chimica Acta, 1922 , vol. 5, p. 750
Full Text Show Details
Claisen
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 72
Chemische Berichte, 1925 , vol. 58, p. 279 Anm. 15
反应条件
(i) Mg, Et2O, (ii) /BRN= 1420778/; Multistep reaction;
参考文献
Chevalier,P. et al.
Bulletin de la Societe Chimique de France, 1975 , p. 2254 - 2258
反应条件
1.1: magnesium; ethylene dibromide / tetrahydrofuran / 2.5 h / Inert atmosphere; Reflux
1.2: 0 - 20 °C / Inert atmosphere
2.1: water; mercury(II) trifluoroacetate / tetrahydrofuran / 1.5 h / 20 °C / Inert atmosphere
2.2: 0.5 h / Inert atmosphere
View Scheme
参考文献
Braddock, D. Christopher; Marklew, Jared S.; Thomas, Alexander J. F.
Chemical Communications, 2011 , vol. 47, # 32 p. 9051 - 9053
