1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
lithium hydroxide; 1-n-butyl-3-methylimidazolium tetrafluoroborate
T=20°C; 10 h;
参考文献
Kryshtal; Zhdankina; Zlotin
Russian Chemical Bulletin, 2004 , vol. 53, # 3 p. 652 - 658
反应条件
in tetrahydrofuran
in terms of catalysts, reagents, and temperature; Product distribution;
参考文献
Cuvigny, Therese; Julia, Marc
Journal of Organometallic Chemistry, 1987 , vol. 331, # 1 p. 121 - 138
反应条件
1: para-methylacetophenone With sodium hydride in N,N-dimethyl-formamide
T=-20°C; 0.333333 h;
2: prenyl bromide in N,N-dimethyl-formamide
T=-20 - 20°C; 1.33333 h;
参考文献
Narender, Tadigoppula; Sarkar, Satinath; Rajendar, Kandikonda; Tiwari, Sriniwas
Organic Letters, 2011 , vol. 13, # 23 p. 6140 - 6143
反应条件
1: acetoacetic acid methyl ester With sodium hydride in tetrahydrofuran; mineral oil
T=0°C; 0.166667 h;
2: With n-butyllithium in tetrahydrofuran; mineral oil
0.166667 h;
3: prenyl bromide in tetrahydrofuran; mineral oil
0.0833333 h;
参考文献
Resek, James E.
Journal of Organic Chemistry, 2008 , vol. 73, # 24 p. 9792 - 9794
参考文献
Funakoshi, Kazuhisa; Togo, Nagako; Sakai, Kiyoshi
Tetrahedron Letters, 1989 , vol. 30, # 9 p. 1095 - 1098
反应条件
1: 58 percent / NaH / toluene / 1 h / 20 °C
2: 96 percent / 4-(dimethylamino)pyridine / CH2Cl2 / 4 h / Heating
3: 93 percent / Et3N; tri(o-tolyl)phosphine / Pd(OAc)2 / toluene / 20 h / Heating
4: 74 percent / KOH / H2O; methanol / 3 h / Heating
View Scheme
参考文献
Uto, Yoshihiro; Ae, Shutaro; Koyama, Daisuke; Sakakibara, Mitsutoshi; Otomo, Naoki; Otsuki, Mamoru; Nagasawa, Hideko; Kirk, Kenneth L.; Hori, Hitoshi
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5721 - 5728
反应条件
potassium carbonate in acetone
5 h; Heating;
参考文献
Daskiewicz, Jean-Baptiste; Depeint, Flore; Viornery, Lionel; Bayet, Christine; Comte-Sarrazin, Geraldine; Comte, Gilles; Gee, Jennifer M.; Johnson, Ian T.; Ndjoko, Karine; Hostettmann, Kurt; Barron, Denis
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2790 - 2804
反应条件
indium in water
T=0°C;
参考文献
Bryan, Vernal J.; Chan, Tak-Hang
Tetrahedron Letters, 1997 , vol. 38, # 37 p. 6493 - 6496
反应条件
1: 95 percent / K2CO3 / dimethylformamide / 96 h / Ambient temperature
2: 90 percent / CuSO4*5H2O / methanol; H2O / 1 h / Heating
3: 95 percent / NaOMe / methanol / 24 h / Ambient temperature
View Scheme
参考文献
Masson, Serge; Thuillier, Andre
Tetrahedron Letters, 1982 , vol. 23, # 40 p. 4087 - 4090
反应条件
methanol; diethyl ether; sodium methylate
参考文献
Riedl
Chemische Berichte, 1952 , vol. 85, p. 692,704, 708
