1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
1: diethyl ether
2: hydrogen chloride / anschliessend mit wss. Salzsaeure
3: diethyl ether; mercury (II)-chloride
View Scheme
参考文献
Lewina et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2236,2237;engl.Ausg.S.2202,2204
反应条件
1: diethyl ether
2: nickel-aluminium oxide / 170 - 180 °C / Hydrogenation
View Scheme
参考文献
Lewina et al.
Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 2825,2827;engl.Ausg.S.2849,2850
反应条件
1: diethyl ether
2: nickel / aluminium oxide / 170 °C / Hydrogenation
View Scheme
参考文献
Lewina et al.
Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 2825,2827;engl.Ausg.S.2849,2850
反应条件
1: diethyl ether
2: hydrogen chloride / beim anschliessenden Behandeln mit wss. Salzsaeure
3: diethyl ether; mercury (II)-chloride
View Scheme
参考文献
Lewina et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2945,2948,2949;engl.Ausg.S.2906,2909,2910
反应条件
1: diethyl ether
2: hydrogen chloride / anschliessend mit wss. Salzsaeure
3: diethyl ether; mercury (II)-chloride
View Scheme
参考文献
Lewina et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2236,2237;engl.Ausg.S.2202,2204
反应条件
1: 2-aminopyridine With sodium amide in toluene
3 h; Reflux;
2: prenyl bromide in toluene
3 h; Reflux;
参考文献
Coxon, Geoffrey D.; Furman, Brian L.; Harvey, Alan L.; McTavish, John; Mooney, Mark H.; Arastoo, Mahmoud; Kennedy, Alan R.; Tettey, Justice M.; Waigh, Roger D.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 11 p. 3457 - 3463
反应条件
1: 1) NaH; 2) n-BuLi / 1) THF, 0 deg C, 15 min; 2) hexane, 0 deg C, 15 min; 3) THF, 5-10 deg C, 45 min
2: 98 percent / triethylamine, tosyl azide / acetonitrile / 10 h / Ambient temperature
View Scheme
参考文献
Roberts, Richard A.; Schuell, Volker; Paquette, Leo A.
Journal of Organic Chemistry, 1983 , vol. 48, # 12 p. 2076 - 2084
反应条件
potassium carbonate in acetone
12 h; Reflux;
参考文献
Patre, Rupesh E.; Shet, Jyoti B.; Parameswaran, Perunninakulath S.; Tilve, Santosh G.
Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6488 - 6490
反应条件
indium; methyllithium
1.) 1,4-dioxane, 2.) 0 deg C, 30 min; room temperature, 2 h, 3.) 1,4-dioxane, 0 deg C, 1 h, room temperature, 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Araki, Shuki; Jin, Shun-Ji; Butsugan, Yasuo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 5 p. 549 - 552
反应条件
ytterbium in tetrahydrofuran
T=20°C; 9 h;
参考文献
Gohain, Mukut; Gogoi, Baikuntha J.; Prajapati, Dipak; Sandhu, Jagir S.
New Journal of Chemistry, 2003 , vol. 27, # 7 p. 1038 - 1040
