1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
Zn/Gr
5 h; Ambient temperature;
参考文献
Marceau, P.; Gautreau, L.; Beguin, F.; Guillaumet, G.
Journal of Organometallic Chemistry, 1991 , vol. 403, # 1.2 p. 21 - 27
反应条件
chromium dichloride; lithium iodide in tetrahydrofuran
T=22°C; Hiyama-Nozaki reaction; 0.5 h;
参考文献
Schrekker, Henri S.; De Bolster, Martin W. G.; Orru, Romano V. A.; Wessjohann, Ludger A.
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 1975 - 1981
反应条件
1: indium / tetrahydrofuran; water / 20 °C
2: Jone's reagent / diethyl ether / 1 h / 0 - 20 °C
View Scheme
参考文献
Han, Bing; Yang, Xiu-Long; Fang, Ran; Yu, Wei; Wang, Chao; Duan, Xiao-Yong; Liu, Shuai
Angewandte Chemie - International Edition, 2012 , vol. 51, # 35 p. 8816 - 8820
反应条件
chromium dichloride; lithium iodide in tetrahydrofuran
T=55°C; Hiyama-Nozaki reaction; 3 h; Product distribution; Further Variations:Reaction partnersReagentsTemperatures;
参考文献
Schrekker, Henri S.; De Bolster, Martin W. G.; Orru, Romano V. A.; Wessjohann, Ludger A.
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 1975 - 1981
反应条件
in tetrahydrofuran
in terms of catalysts, reagents, and temperature; Product distribution;
参考文献
Cuvigny, Therese; Julia, Marc
Journal of Organometallic Chemistry, 1987 , vol. 331, # 1 p. 121 - 138
反应条件
1: 95 percent / K2CO3 / dimethylformamide / 96 h / Ambient temperature
2: 90 percent / CuSO4*5H2O / methanol; H2O / 1 h / Heating
View Scheme
参考文献
Stella, Lucien; Amrollah-Madjdabadi, Ali
Synthetic Communications, 1984 , vol. 14, # 12 p. 1141 - 1148
反应条件
potassium carbonate in acetone
6 h; Heating;
参考文献
Devakumar, C.; Saxena, V. S.; Mukerjee, S. K.
Agricultural and Biological Chemistry, 1985 , vol. 49, # 3 p. 725 - 730
反应条件
Montmorillonite K10 in dichloromethane
参考文献
Prado, Soizic; Janin, Yves L.; Saint-Joanis, Brigitte; Brodin, Priscille; Michel, Sylvie; Koch, Michel; Cole, Stewart T.; Tillequin, Francois; Bost, Pierre-Etienne
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 5 p. 2177 - 2186
反应条件
1: 1.) NaH, (iPr)2NH, 2.) n-BuLi / 1.) THF, 0 deg C and reflux, 15 min, 2.) THF, HMPA, 0 deg C, 15 min and 35 deg C 30 min, 3.) THF, HMPA, 0 deg C and 3 h, 25 deg C
2: 91 percent / LiAlH4 / diethyl ether / 10 h / 0 °C
3: Et3N / CH2Cl2 / 1 h / 0 °C
4: NaI / acetone / 12 h / Heating
View Scheme
参考文献
Cocker, Wesley; Geraghty, Niall W. A.; McMurry, T. Brian H.; Shannon, Patrick V. R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 10 p. 2245 - 2254
反应条件
1: aq. NaOH, <PhCH2NEt3>Cl
2: aq. NaOH, <PhCH2NEt3>Cl / CHBr3 / 4 h / 55 - 60 °C
View Scheme
参考文献
Baird,M.S. et al.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 210 - 211
