1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
1: ethyl acetoacetate With sodium hydride
T=0°C;
2: With n-butyllithium
T=0°C;
3: prenyl bromide in tetrahydrofuran
T=0 - 20°C;
参考文献
Wessjohann, Ludger A.; Fulhorst, Michael; Zakharova, Svetlana
Polish Journal of Chemistry, 2006 , vol. 80, # 4 p. 673 - 678
反应条件
1: enolate sodique de l'acetylacetate d'ethyle With n-butyllithium in tetrahydrofuran; cyclohexane
T=0°C; 0.5 h;
2: prenyl bromide in tetrahydrofuran; cyclohexane
0.5 h; Further stages.;
参考文献
Rawat, Diwan S; Gibbs, Richard A
Organic letters, 2002 , vol. 4, # 18 p. 3027 - 3030
反应条件
potassium hydroxide; dibenzo-18-crown-6 in toluene
T=50 - 60°C; 2 h;
参考文献
Zakharkin, L. I.; Churilova, I. M.; Ovseenko, S. T.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 9.2 p. 1696 - 1699
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 9 p. 1962 - 1966
参考文献
Snider,B.B. et al.
Tetrahedron Letters, 1979 , p. 1679 - 1682
反应条件
1: tetrahydrofuran / 1 h / 20 °C / |Inert atmosphere
2: tetrahydrofuran / 20 h / |Reflux; |Inert atmosphere
View Scheme
参考文献
Zhao, Li-Ming; Wan, Li-Jing; Zhang, Shu-Qing; Sun, Rui; Ma, Feng-Yan
Tetrahedron, 2013 , vol. 69, # 37 p. 7970 - 7974
反应条件
chromium dichloride; lithium iodide in tetrahydrofuran
T=22°C; Hiyama-Nozaki reaction; 0.5 h;
参考文献
Schrekker, Henri S.; De Bolster, Martin W. G.; Orru, Romano V. A.; Wessjohann, Ludger A.
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 1975 - 1981
反应条件
chromium dichloride; lithium iodide in tetrahydrofuran
T=55°C; Hiyama-Nozaki reaction; 3 h; Product distribution; Further Variations:Reaction partnersReagentsTemperatures;
参考文献
Schrekker, Henri S.; De Bolster, Martin W. G.; Orru, Romano V. A.; Wessjohann, Ludger A.
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 1975 - 1981
反应条件
beim Ozonisieren und nachfolgenden Oxydieren mit Permanganat;
参考文献
Staudinger; Kreis; Schilt
Helvetica Chimica Acta, 1922 , vol. 5, p. 750
参考文献
Staudinger; Kreis; Schilt
Helvetica Chimica Acta, 1922 , vol. 5, p. 750
Full Text Show Details
Claisen
Justus Liebigs Annalen der Chemie, 1925 , vol. 442, p. 227
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 105, p. 66
