1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
1: (i) NaH, nBuLi, (ii) /BRN= 1420778/ 2: TsOH View Scheme
参考文献
Casey,C.P.; Marten,D.F.
Synthetic Communications, 1973 , vol. 3, p. 321 - 324
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=0 - 20°C; Alkylation;
参考文献
Breslin, Henry J.; Kukla, Michael J.; Kromis, Teresa; Cullis, Heather; De Knaep, Fons; Pauwels, Rudi; Andries, Koen; De Clercq, Erik; Janssen, Marcel A.C.; Janssen, Paul A.J.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 11 p. 2427 - 2436
反应条件
2: LiAlH4 View Scheme
参考文献
Pala,G. et al.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 3 p. 556 - 557
反应条件
2: LiAlH4 View Scheme
参考文献
Pala,G. et al.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 3 p. 556 - 557
反应条件
potassium carbonate in acetone 2 h; Heating;
参考文献
Epifano, Francesco; Menghini, Luigi; Pagiotti, Rita; Angelini, Paola; Genovese, Salvatore; Curini, Massimo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5523 - 5525
反应条件
potassium carbonate; acetone Erwaermen des Reaktionsprodukts mit methanol. Kalilauge;
参考文献
Lauer; Moe
Journal of the American Chemical Society, 1943 , vol. 65, p. 289,292
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=0 - 20°C; Alkylation; 192 h;
参考文献
Breslin, Henry J.; Kukla, Michael J.; Kromis, Teresa; Cullis, Heather; De Knaep, Fons; Pauwels, Rudi; Andries, Koen; De Clercq, Erik; Janssen, Marcel A.C.; Janssen, Paul A.J.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 11 p. 2427 - 2436
反应条件
sodium acetate; acetic acid
参考文献
Pochini,A. et al.
Gazzetta Chimica Italiana, 1975 , vol. 105, p. 1245 - 1252
反应条件
2: LiAlH4 View Scheme
参考文献
Pala,G. et al.
Journal of Medicinal Chemistry, 1970 , vol. 13, # 3 p. 556 - 557
反应条件
sodium acetate; acetic acid
参考文献
Pochini,A. et al.
Gazzetta Chimica Italiana, 1975 , vol. 105, p. 1245 - 1252
