1: 1-methylguanidine hydrochloride With sodium methylate in methanol T=20°C; 0.5 h; 2: (E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one in methanol T=50°C; 24 h;

1: guanidine hydrochloride With sodium in methanol T=20°C; 0.5 h; Inert atmosphere; 2: (E)-1-(2-chloropyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one in methanol T=50°C; 24 h;