4-溴-1H-吡咯并[2,3-c]吡啶-2-羧酸甲酯合成路线 （共 2 条）
反应条件
1: 77 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / CH2Cl2 / 2 h / 20 °C
2: 85 percent / K2CO3; L-proline / CuI / dioxane / 24 h / 100 °C
View Scheme
参考文献
Barberis, Claude; Gordon, Thomas D.; Thomas, Christine; Zhang, Xiaolei; Cusack, Kevin P.
Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8877 - 8880
反应条件
1: 19 percent / NaOMe / methanol / 40 h / 0 °C
2: 44 percent / decahydronaphthalene / 0.17 h / 191 °C
View Scheme
参考文献
Roy, Patrick J.; Dufresne, Claude; Lachance, Nicolas; Leclerc, Jean-Philippe; Boisvert, Michel; Wang, Zhaoyin; Leblanc, Yves
Synthesis, 2005 , # 16 art. no. M03305SS, p. 2751 - 2757
