6-溴-1,2,3,4-四氢二苯并[B,D]噻吩合成路线 （共 3 条）
参考文献
Hardcastle, Ian R.; Cockcroft, Xiaoling; Curtin, Nicola J.; El-Murr, Marine Desage; Leahy, Justin J. J.; Stockley, Martin; Golding, Bernard T.; Rigoreau, Laurent; Richardson, Caroline; Smith, Graeme C. M.; Griffin, Roger J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 24 p. 7829 - 7846
反应条件
1: 78 percent / aq. NaOH / ethanol / 16 h / Heating
2: 81 percent / polyphosphoric acid; PO5 / 0.5 h / 180 °C
View Scheme
参考文献
Hardcastle, Ian R.; Cockcroft, Xiaoling; Curtin, Nicola J.; El-Murr, Marine Desage; Leahy, Justin J. J.; Stockley, Martin; Golding, Bernard T.; Rigoreau, Laurent; Richardson, Caroline; Smith, Graeme C. M.; Griffin, Roger J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 24 p. 7829 - 7846
反应条件
1: 78 percent / aq. NaOH / ethanol / 16 h / Heating
2: 81 percent / polyphosphoric acid; PO5 / 0.5 h / 180 °C
View Scheme
参考文献
Hardcastle, Ian R.; Cockcroft, Xiaoling; Curtin, Nicola J.; El-Murr, Marine Desage; Leahy, Justin J. J.; Stockley, Martin; Golding, Bernard T.; Rigoreau, Laurent; Richardson, Caroline; Smith, Graeme C. M.; Griffin, Roger J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 24 p. 7829 - 7846
