3-(三氟甲基)吡嗪-2-羧酸甲酯合成路线 （共 3 条）
反应条件
potassium fluoride; copper(l) chloride in N,N-dimethyl-formamide
T=120°C; 12 h;
参考文献
DOW AGROSCIENCES LLC
Patent: US2011/301178 A1, 2011 ;
Location in patent: Page/Page column 8 ;
反应条件
potassium fluoride; copper(l) iodide in N,N-dimethyl-formamide
T=115°C; 5 h;
参考文献
NIHON NOHYAKU CO., LTD.
Patent: EP1757595 A1, 2007 ;
Location in patent: Page/Page column 24 ;
反应条件
1: With potassium hydroxide; ethanol; water
1 h; Heating / reflux;
2: With hydrogenchloride; water in ethanol
参考文献
NIHON NOHYAKU CO., LTD.
Patent: EP1757595 A1, 2007 ;
Location in patent: Page/Page column 24-25 ;
