(R)-4-吗啉-1-(苯基硫代)-2-丁基胺合成路线 (共 2 条)
反应条件
N-ethyl-N,N-diisopropylamine in dimethyl sulfoxide T=20°C; 16 h;
参考文献
Synthesis, , # 15 art. no. F04408SS, p. 2398 - 2404
反应条件
1: With borane-THF in tetrahydrofuran; methanol
T=55°C; 19 h;
2: With hydrogenchloride in methanol
24 h; Heating / reflux;
参考文献
Elmore, Steven W.; Bruncko, Milan; Park, Cheol-Min
Patent: US2005/272744 A1, 2005 ;
Location in patent: Page/Page column 20-21 ;
US 20050272744 A1