2-氨基-1-(1H-吲哚-3-基)乙酮合成路线 （共 7 条）
反应条件
1: 21 percent / Br2 / formic acid; acetic acid / 0.33 h / 23 °C 2: p-xylene; ethanol / 130 °C 3: O2 / p-xylene; ethanol / 24 h / 20 °C View Scheme
参考文献
Miyake, Fumiko Y.; Yakushijin, Kenichi; Home, David A.
Organic Letters, 2000 , vol. 2, # 20 p. 3185 - 3187
反应条件
palladium on activated charcoal; hydrogen in acetic acid
参考文献
Horne, David A.
Patent: US2003/232988 A1, 2003 ;
Location in patent: Page column 0096 ;
反应条件
1: With hydrogenchloride; water in methanol
T=60°C; 72 h; Inert atmosphere;
2: With ammonia in methanol; dichloromethane
参考文献
Miyake, Fumiko; Hashimoto, Michinao; Tonsiengsom, Sorasaree; Yakushijin, Kenichi; Horne, David A.
Tetrahedron, 2010 , vol. 66, # 26 p. 4888 - 4893
参考文献
Mingoia
Gazzetta Chimica Italiana, 1931 , vol. 61, p. 646
反应条件
trifluoroacetic acid
deprotection;
参考文献
Barret, Roland; Roue, Nathalie
Tetrahedron Letters, 1999 , vol. 40, # 20 p. 3889 - 3890
反应条件
1: Yonemitsu procedure
2: trifluoroacetic acid
View Scheme
参考文献
Barret, Roland; Roue, Nathalie
Tetrahedron Letters, 1999 , vol. 40, # 20 p. 3889 - 3890
反应条件
hydrogenchloride in ethanol
Inert atmosphere;
参考文献
Miyake, Fumiko; Hashimoto, Michinao; Tonsiengsom, Sorasaree; Yakushijin, Kenichi; Horne, David A.
Tetrahedron, 2010 , vol. 66, # 26 p. 4888 - 4893
