反应条件
1: With [bis(2-methoxyethyl)amino]-sulfur trifluoride in dichloromethane T=-20°C; 0.5 h; 2: With trichloromonobromomethane; 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=2 - 3°C; 8 h; 3: With sodium hydrogencarbonate in dichloromethane; water
参考文献
ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC.
Patent: WO2004/14881 A2, 2004 ;
Location in patent: Page 163-164 ;
WO 2004/014881 A2
