反应条件
1: 1.) n-BuLi, 2.) HMPA / 1.) THF, hexane, 0 deg C, 10 min, 2.) THF, hexane, 0 deg C, 1.5 h
2: 88 percent / H2 / 10percent Pd/C / diethyl ether / 16 h
3: 44 percent / molecular sieves 4 A, pyridinum dichromate / dimethylformamide / 120 h / Ambient temperature
4: 94 percent / 10percent aq. tetrabutylammonium hydroxide / CH2Cl2 / 16 h
View Scheme
参考文献
Wallace, Paul A.; Minnikin, David E.; McCrudden, Katharine; Pizzarello, Andrea
Chemistry and Physics of Lipids, 1994 , vol. 71, # 2 p. 145 - 162
