1: oxalyl chloride; DMF / CH2Cl2 / 2 h / 20 °C
2: CH2Cl2; dimethylformamide
3: KOH / ethanol / 0.25 h / 20 °C
4: 68 percent / EDCI; HOBt / tetrahydrofuran / 12 h
5: 100 percent / CH2Cl2 / 2 h / 20 °C
6: 55 percent / Et3N / acetonitrile / 6 h / 20 °C
View Scheme
参考文献
Leleu, Stephane; Penhoat, Mael; Bouet, Alexis; Dupas, Georges; Papamicael, Cyril; Marsais, Francis; Levacher, Vincent
Journal of the American Chemical Society, 2005 , vol. 127, # 45 p. 15668 - 15669
