4-羟基-3-硝基-5-丙氧基-苯甲醛合成路线 （共 3 条）
反应条件
1: With AlCl3, aluminium chloride in dichloromethane
T=0 - 50°C;
2: With hydrogenchloride; water in dichloromethane
参考文献
N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian
Patent: WO2011/38204 A1, 2011 ;
Location in patent: Page/Page column 156 ;
WO 2011/038204 A1
反应条件
1: hydrogen bromide; acetic acid / 17 h / 90 °C
2: potassium carbonate / N,N-dimethyl-formamide / 80 °C
3: AlCl3, aluminium chloride / dichloromethane / 0 - 50 °C
View Scheme
参考文献
N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian
Patent: WO2011/38204 A1, 2011 ;
WO 2011/038204 A1
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 80 °C
2: AlCl3, aluminium chloride / dichloromethane / 0 - 50 °C
View Scheme
参考文献
N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian
Patent: WO2011/38204 A1, 2011 ;
WO 2011/038204 A1
